Research

I investigate sleep, neurodegeneration, and brain clearance using MRI. This research includes a central role in coordinating international consortia, focussed on pooling imaging data to improve power, reproducibility, and diversity across datasets. I actively promote open science through my research, collaborations, and outreach initiatives aimed at the broader community.

Research Areas

MRI

Advanced MRI methods to study brain structure, function, and physiology in health and disease.

Sleep and sleep disorders

Sleep disorders, with a focus on narcolepsy and other central disorders of hypersomnolence, REM sleep behaviour disorder, and the effects of sleep and sleep deprivation.

Neurodegeneration

MRI-based investigation of brain changes in neurodegenerative diseases, including Parkinson’s disease and dementia with Lewy bodies.

Brain clearance

MRI-based investigation of brain clearance processes at the intersection of sleep and neurodegeneration.

Large, multi-site datasets

Central role in coordinating international consortia, focussed on pooling imaging data to improve power, reproducibility, and diversity across datasets.

Open science

Promotion of open and reproducible research through transparent methods, open code, inclusive collaboration, and public outreach and teaching

Current Projects

REMIND

Perivascular spaces and sleep in Lewy body disease

Progress 40%

Status: Data collected, preregistration being drafted

NICHY

Brain morphology in central disorders of hypersomnolence

Progress 60%

Status: Preregistration available, guiding collaborating sites with MRI processing

ENIGMA-PD

Neuropsychiatry and brain morphology in Parkinson's disease

Progress 75%

Status: Currently receiving data from sites!

Hypersomnia Nap Study

Neurovascular coupling during sleep stages (including NREM3 and REM!)

Progress 80%

Status: Preregistration available, first analyses done, further analysis ideas being brainstormed!

Consortia & Networks

ENIGMA-PD Site coordinator, data analyst, open science lead

Worldwide consortium pooling neuroimaging data to study brain changes in Parkinson's disease.

NICHY Co-founder, site coordinator, MRI processing lead

Global multi-site neuroimaging consortium focused on central disorders of hypersomnolence.

Dutch Society for Sleep-Wake Research (NSWO) Early Career Researchers Committee Member (2023-2026)

National society promoting sleep research and clinical practice in the Netherlands.

Organization for Human Brain Mapping (OHBM) Secretary, Open Science Special Interest Group (2024-present)

International organisation dedicated to the use of neuroimaging to discover the organisation of the human brain.